Lidocaine Prilocaine Cream versus LidocaineHCL Injection for Pain Relief during Second Degree of Perineal Tear Suturing after Vaginal Delivery: A Comparative Study

Lidokain Prilokain Topikal versus Injeksi LidokainHCL dalam Menghilangkan Nyeri Selama Penjahitan Luka Perineum Tingkat Dua Pascapersalinan Pervaginam: Sebuah Studi Komparatif

  • Rahmawati Rahmawati Faculty of Medicine Universitas Hasanuddin Makassar
  • David Lotisna Faculty of Medicine Universitas Hasanuddin Makassar
  • Nusratuddin Abdullah Faculty of Medicine Universitas Hasanuddin Makassar
  • Maisuri T Chalid Faculty of Medicine Universitas Hasanuddin Makassar
  • Telly Tessy Faculty of Medicine Universitas Hasanuddin Makassar

Abstract

Abstract

Objective : To compare the effectiveness of topically applied lidocaine-prilocaine cream with lidocaine-HCl injection in the reduction of pain during second degree of perineal tear suturing after vaginal delivery.

Methods : One hundred and twenty-four of women with second degree of perineal tear after vaginal delivery were enrolled in this randomized clinical trial. Women were assigned randomly to have either application of lidocaine-prilocaine cream (n=62) or local injection of lidocaine-HCl (n=62) for anesthetic during perineal suturing. Pain measured with viasual analog scale (VAS) for the first 5 minutes during the perineal suturing. Statistical analysis was performed by comparative analytic numerical unpaired with independent t test between the two groups and significance was assessed at p<0.05. Data were presented as mean ± standard deviation (SD).

Results : There was no significantly different of pain score between lidocaine-prilocaine cream and lidocaine-HCl injection group (5.66±1.07 vs 5.56±1.5; p=0.473).

Conclusion : Application of lidocaine-prolicaine cream as effective as injection of lidocaine for reducing pain during second degree of perineal tear suturing after vaginal delivery.

Keywords : Lidocaine-prilocaine cream, lidocaine-HCl injection, pain, perineal suturing, vaginal delivery

 

 

Abstrak

Tujuan: Untuk membandingkan efektivitas antara lidokain-prilokain topikal dan lidokain-HCl injeksi dalam mengurangi nyeri selama penjahitan luka perineum tingkat dua setelah persalinan normal.

Metode: Seratus dua puluh empat perempuan dengan robekan perineum tingkat dua postpartum pervaginam mengikuti uji coba klinis secara acak ini. Enam puluh dua perempuan (n=62) menggunakan lidokain-prilokain topikal dan 62 perempuan lainnya (n=62) menggunakan injeksi lokal lidokain-HCl untuk anestesi selama penjahitan perineum. Nyeri diukur dengan visual analog scale (VAS) untuk 5 menit pertama selama penjahitan perineum. Analisis statistik dilakukan dengan uji numerik komparatif tidak berpasangan dengan uji t independen antara kedua kelompok dengan tingkat kemaknaan p<0,05. Data disajikan sebagai rerata ± standar deviasi (SD).

Hasil: Tidak terdapat perbedaan signifikan skor nyeri antara kelompok  lidokain-prilokain topikal dan kelompok injeksi lidokain-HCl (5,66 ± 1,07 vs 5,56 ± 1,5; p = 0,473).

Kesimpulan : Efektifitas lidokain-prolikain topikal untuk mengurangi nyeri sama dengan injeksi lidokain-HCl selama penjahitan robekan perineum tingkat dua postpartum pervaginam.

Kata kunci : Lidokain-prolikain topical, lidokain-HCl injeksi, nyeri, penjahitan perineum, persalinan normal

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Author Biographies

David Lotisna, Faculty of Medicine Universitas Hasanuddin Makassar

Departement of Obstetrics and Gynecology

Nusratuddin Abdullah, Faculty of Medicine Universitas Hasanuddin Makassar

Department of Obstetrics and Gynecology

Maisuri T Chalid, Faculty of Medicine Universitas Hasanuddin Makassar

Departement of Obstetrics and Gynecology

Telly Tessy, Faculty of Medicine Universitas Hasanuddin Makassar

Departement Obstetrics and Gynecology

Published
2018-10-12
Section
Research Article