A Comparative Study of Nomegestrol Acetate and a Combination of Ethinylestradiol and Levonorgestrel for Delaying Menstruation among Umrah Pilgrims

Abstract

Objective: To compare the effectiveness efficacy of nomegestrol
acetate with and combination of ethinylestradiol and levonorgestrel
as a regimen for delaying menstruation in Umrah pilgrims in Palembang
city.
Methods: This single-blind randomized controlled trial was conducted
in Hajj and Umrah Guidance Group in Palembang city during
December 2016 to January 2017. Population of this study was 30
women who meet the inclusion and exclusion criteria. Frequency
and distribution of data was described in a table. Effectiveness and
the side effects treatment between the two groups were analyzed
with Chi Square test. Data was were analyzed using SPSS version
18.0.
Results: There were no differences in age, education, occupation,
parity, body weight, height and contraceptive history between
two both groups (all p values > 0.05). Statistical analysis showed
there was no difference in spotting between nomegestrol acetate
5 mg or a combination of levonorgestrel 150 mcg and 30 mcg
ethinylestradiol in Umrah pilgrims (p = 1.000). Other side effects
such as (dizziness, depression, breast tenderness, heavy limbs,
nauseam and vomiting) between the two groups could not be
analyzed because all subjects did not experience any other side
effects.
Conclusion: There is no difference in effectiveness between
nomegestrol acetate 5 mg or combination of levonorgestrel 150
mcg and 30 mcg ethinylestradiol as a regimen for delaying
menses in Umrah pilgrims in Palembang city.
[Indones J Obstet Gynecol 2018; 6-1: 45-49]
Keywords: delay menstruation, ethinylestradiol, levonorgestrel,
nomegestrol, side effects, spotting, umrah