Promising Male Hormonal Contraceptive are Well Established Soon a Reality

  • Eka R Gunardi Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta
  • Arnold Soetarso Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta
  • Putri Addina Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta

Abstract

Objective: To understand the modalities used for male hormonal contraception. Methods: Literature review Conclusion: Male contraceptive methods are still limited but hormonal contraceptive methods are being developed. The basic mechanism of male hormonal contraception is to inhibit spermatogenesis by suppression of the hypothalamic-pituitary-testicular axis function. Administration of testosterone or androgen derivative that is given in combination with progestin or GnRH antagonist shows that male hormonal contraceptive is reversible, effective, and acceptable as a male contraceptive method. However, no method of male hormonal contraceptive is ready for clinical use and marketed due to limited studies. [Indones J Obstet Gynecol 2015; 3-4: 239-243] Keywords: GnRH antagonist, male hormonal contraceptive, progestin, testosterone

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Author Biographies

Eka R Gunardi, Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta
Department of Obstetrics and Gynecology
Arnold Soetarso, Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta
Department of Obstetrics and Gynecology
Putri Addina, Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta
Department of Obstetrics and Gynecology
Published
2015-10-14
Section
Systematic Review