Lidocaine Prilocaine Cream versus LidocaineHCL Injection for Pain Relief during Second Degree of Perineal Tear Suturing after Vaginal Delivery: A Comparative Study

Lidokain Prilokain Topikal versus Injeksi LidokainHCL dalam Menghilangkan Nyeri Selama Penjahitan Luka Perineum Tingkat Dua Pascapersalinan Pervaginam: Sebuah Studi Komparatif

  • Rahmawati Rahmawati Faculty of Medicine Universitas Hasanuddin Makassar
  • David Lotisna Faculty of Medicine Universitas Hasanuddin Makassar
  • Nusratuddin Abdullah Faculty of Medicine Universitas Hasanuddin Makassar
  • Maisuri T Chalid Faculty of Medicine Universitas Hasanuddin Makassar
  • Telly Tessy Faculty of Medicine Universitas Hasanuddin Makassar

Abstract

Abstract
Objective : To compare the effectiveness of topically applied lidocaine-prilocaine cream with lidocaine-HCl injection in the reduction of pain during second degree of perineal tear suturing after vaginal delivery.
Methods : One hundred and twenty-four of women with second degree of perineal tear after vaginal delivery were enrolled in this randomized clinical trial. Women were assigned randomly to have either application of lidocaine-prilocaine cream (n=62) or local injection of lidocaine-HCl (n=62) for anesthetic during perineal suturing. Pain measured with viasual analog scale (VAS) for the first 5 minutes during the perineal suturing. Statistical analysis was performed by comparative analytic numerical unpaired with independent t test between the two groups and significance was assessed at p<0.05. Data were presented as mean ± standard deviation (SD).
Results : There was no significantly different of pain score between lidocaine-prilocaine cream and lidocaine-HCl injection group (5.66±1.07 vs 5.56±1.5; p=0.473).
Conclusion : Application of lidocaine-prolicaine cream as effective as injection of lidocaine for reducing pain during second degree of perineal tear suturing after vaginal delivery.
Keywords : Lidocaine-prilocaine cream, lidocaine-HCl injection, pain, perineal suturing, vaginal delivery
 
 
Abstrak
Tujuan: Untuk membandingkan efektivitas antara lidokain-prilokain topikal dan lidokain-HCl injeksi dalam mengurangi nyeri selama penjahitan luka perineum tingkat dua setelah persalinan normal.
Metode: Seratus dua puluh empat perempuan dengan robekan perineum tingkat dua postpartum pervaginam mengikuti uji coba klinis secara acak ini. Enam puluh dua perempuan (n=62) menggunakan lidokain-prilokain topikal dan 62 perempuan lainnya (n=62) menggunakan injeksi lokal lidokain-HCl untuk anestesi selama penjahitan perineum. Nyeri diukur dengan visual analog scale (VAS) untuk 5 menit pertama selama penjahitan perineum. Analisis statistik dilakukan dengan uji numerik komparatif tidak berpasangan dengan uji t independen antara kedua kelompok dengan tingkat kemaknaan p<0,05. Data disajikan sebagai rerata ± standar deviasi (SD).
Hasil: Tidak terdapat perbedaan signifikan skor nyeri antara kelompok  lidokain-prilokain topikal dan kelompok injeksi lidokain-HCl (5,66 ± 1,07 vs 5,56 ± 1,5; p = 0,473).
Kesimpulan : Efektifitas lidokain-prolikain topikal untuk mengurangi nyeri sama dengan injeksi lidokain-HCl selama penjahitan robekan perineum tingkat dua postpartum pervaginam.
Kata kunci : Lidokain-prolikain topical, lidokain-HCl injeksi, nyeri, penjahitan perineum, persalinan normal

Author Biographies

David Lotisna, Faculty of Medicine Universitas Hasanuddin Makassar
Departement of Obstetrics and Gynecology
Nusratuddin Abdullah, Faculty of Medicine Universitas Hasanuddin Makassar
Department of Obstetrics and Gynecology
Maisuri T Chalid, Faculty of Medicine Universitas Hasanuddin Makassar
Departement of Obstetrics and Gynecology
Telly Tessy, Faculty of Medicine Universitas Hasanuddin Makassar
Departement Obstetrics and Gynecology
Published
2018-10-12
How to Cite
RAHMAWATI, Rahmawati et al. Lidocaine Prilocaine Cream versus LidocaineHCL Injection for Pain Relief during Second Degree of Perineal Tear Suturing after Vaginal Delivery: A Comparative Study. Indonesian Journal of Obstetrics and Gynecology, [S.l.], p. 228 - 231, oct. 2018. ISSN 2338-7335. Available at: <http://inajog.com/index.php/journal/article/view/846>. Date accessed: 12 nov. 2018. doi: https://doi.org/10.32771/inajog.v6i4.846.
Section
Research Article