The Correlation between Calcium Serum and Calcium Urine Level with the Blood Pressure in Preeclampsia

  • Deni W. Suryono Department of Obstetrics and Gynecology Faculty of Medicine University of Padjadjaran/ Dr. Hasan Sadikin Hospital Bandung

Abstract

Objective: To analyze the differences of calcium serum and calcium urine level in preeclampsia and normal pregnancy, and to analyze the correlation between calcium serum and calcium urine level with blood pressure. Method: This study is a cross sectional study with 44 women with preeclampsia and 45 women with normal pregnancies, that meet our inclusion criteria. The samples were obtained from Dr. Hasan Sadikin Hospital and six satellite hospitals from June to September 2011. The comparison of mean calcium serum and calcium urine level of the preeclampsia group was calculated using Mann-Whitney test, and the correlation between calcium serum and calcium urine level and preeclampsia were calculated using Rank Spearman correlation test. Result: The result of the characteristic test in two groups of study shows that both groups are homogenic and comparable. The mean of calcium serum level in women with preeclampsia (7.97 mg/dl) is lower than in normal pregnancy (8.82 mg/dl) with p<0.0001 and the mean of calcium urine level in women with preeclampsia (1.725 mg/dl) is lower than normal pregnancy (2.809 mg/dl) with p<0.0001. There is a negative correlation between calcium serum level (rs = –0,62; p<0,001) and calcium urine level (rs = –0,68; p<0,001) with systolic pressure in preeclampsia. There is also a negative correlation between calcium serum level (rs = –0,65; p<0,001) and calcium urine level (rs = –0,68; p<0,001) with diastolic pressure in preeclampsia. Conclusion: There is a negative correlation between calcium serum level and calcium urine level with systolic and diastolic pressure in preeclampsia, meaning that the lower the calcium serum and calcium urine level is, the higher systolic and diastolic pressure. [Indones J Obstet Gynecol 2012; 36-1:3-7] Keywords: blood pressure, calcium blood level, calcium urine level, preeclampsia

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Published
2016-12-16